Mechanisms of protein aggregation.
نویسندگان
چکیده
Aggregation or reversible self-association of protein therapeutics can arise through a number of different mechanisms. Five common aggregation mechanisms are described and their relations to manufacturing processes to suppress and remove aggregates are discussed.
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عنوان ژورنال:
- Current pharmaceutical biotechnology
دوره 10 4 شماره
صفحات -
تاریخ انتشار 2009